A Deep Dive into the Top 30 Sad and Depressed Anime Girls

Anime has always been a medium to convey deep emotions and profound stories, and sad and depressed characters are no exception. These characters often impact viewers, eliciting emotions from sympathy and empathy to heartbreak and sorrow.

This blog post will explore the top 30 sad and depressed anime girls. These characters represent some of the most emotionally charged storylines in anime, and their struggles and hardships will undoubtedly leave a mark on anyone who watches their stories unfold.

Whether you’re looking for a relatable character to connect with or simply appreciate the emotional depth of these complex characters, this list will undoubtedly offer something for everyone. So, let’s dive into the world of these heart-wrenching anime girls and explore their poignant stories.

Sad & Depressed Anime Girls Of All Time

So if you’re in the mood for a good cry (or want to see some strong female characters), this list is for you. So without further ado, let’s look at some of the saddest and most depressed anime girls out there!

1. Shouko Nishimiya from Koe no Katachi

Depressed Anime Girls

Shouko Nishimiya is the main protagonist of Koe no Katachi and one of the saddest and most depressed anime girls of all time.

She was born with a hearing disability, so she was constantly ridiculed and bullied by her classmates throughout her childhood. This eventually led to her transferring schools, but bullies still targeted her.

As a result of all the bullying she endured, Shouko has developed a very negative view of herself and the world around her. She is highly introverted and doesn’t have any friends. The only person who seems to care for her is her older sister, Miyoko.

Despite all the hardships she’s gone through in her life, Shouko is still a kind and caring person. She always tries to help others, even if it means putting herself in danger.

She also has a strong determination to try and overcome her disability, even though it seems like an impossible task.

If you’re looking for an anime girl who will make you feel sad and depressed, then look no further than Shouko Nishimiya from Koe no Katachi!

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2. Haruka Kotoura from Kotoura San

Depressed Anime Girls

Haruka Kotoura is a character who embodies the pain of loneliness and isolation in the anime world. As a girl with psychic abilities, Haruka can read people’s thoughts, ironically making her struggle to form genuine connections with others. Her powers have made her an outcast, leading to her deep sadness and depression.

However, Haruka is a character who refuses to give up on her dreams of finding happiness and love. Despite all her hardships, she remains strong and resilient. Her story is a poignant reminder of the importance of human connection and the power of resilience.

Haruka’s journey from isolation to acceptance and love is a heart-wrenching tale that will undoubtedly impact anyone who watches it. She is a character that anime fans will cherish for her strength and courage in the face of adversity.

3. Homura Akemi from Puella Magi Madoka Magica

Depressed Anime Girls

Homura Akemi is a character from the popular anime series “Puella Magi Madoka Magica,” Her story is one of the most tragic and emotionally charged in the series.

Homura is a time traveler who repeatedly goes back to try to prevent the death of her best friend, Madoka and the ultimate destruction of the world.

Through her journey, Homura experiences deep sadness and depression, constantly struggling against impossible odds and the weight of her guilt and regret. Despite this, she remains a strong and determined character who fights for what she believes in.

Homura’s story is a poignant reminder of the power of love and the lengths people will go to protect those they care about. Her struggles and hardships will undoubtedly leave a lasting impact on anyone who watches her story unfold.

Related: 20 Gyaru Anime Characters That Will Steal Your Heart

4. Violet Evergarden from Violet Evergarden

Depressed Anime Girls

Violet Evergarden has been through a lot in her young life. She was orphaned as a child and then drafted into the army, where she fought in a brutal war.

Violet is a complicated character haunted by her past and struggling to find her place in the world.

While Violet may be one of the saddest and most depressed anime girls of all time, she is also one of the strongest. She is fearless and determined and never gives up on herself or those she cares about.

Violet is an inspiring figure which shows us that overcoming our sadness and building a new life for ourselves is possible.

5. Kikyo from Inuyasha

Depressed Anime Girls

Kikyo is a character from the popular anime series “Inuyasha,” She represents one of the most tragic and emotionally charged storylines in anime.

Kikyo is a priestess who died centuries ago but was brought back to life by a dark sorcerer. As a result of this resurrection, Kikyo is burdened with the memories of her past life and the pain of betrayal by the man she loved, Inuyasha.

Kikyo’s tragic story arc is a poignant exploration of love, betrayal, and redemption themes. Her struggles with her emotions and her complicated relationship with Inuyasha will impact those who watch her story unfold.

Despite her tragic past, Kikyo is a strong and resilient character who refuses to be defined by her pain. Her journey toward forgiveness and acceptance is a testament to the power of the human spirit and the importance of finding peace within oneself.

Anime fans will undoubtedly cherish and admire Kikyo for her unwavering strength and determination.

Related: Beard On Fleek: Top 25 Anime Characters With Beards

6. Enma Ai from from Jigoku Shoujo

Depressed Anime Girls

Enma Ai is the protagonist of Jigoku Shoujo, also known as Hell Girl. She is a beautiful and mysterious girl who seems to be emotionless.

However, she is unfortunate and depressed. Her sadness comes from her tragic past. When she was younger, her parents were killed in a car accident.

This caused her to become very withdrawn and introverted. Enma Ai’s only goal is to get revenge on those who have wronged her. However, she is also very kind and caring, often helping those in need.

7. Annie Leonhart from Attack On Titan

Depressed Anime Girls

Annie Leonhart is one of the most popular girls from Attack on Titan. She is strong, independent, and doesn’t take crap from anyone. But beneath her tough exterior lies a deep sadness and depression.

Annie was born into a wealthy family but never truly loved or accepted by them. Her father was always disappointed in her, and her mother was constantly critical of her. As a result, Annie grew up feeling unloved and worthless.

She eventually ran away from home and joined the Survey Corps, where she found a sense of camaraderie and purpose.

However, her dark despair haunts her, and she struggles to find happiness. Annie’s story is one of tragedy, and pain but also of hope, and strength. She is a complex character that fans can’t help but love.

Related: Top 30 Anime Characters With Hats: A Must-See List!

8. Hotaru Tomoe from Sailor Moon

Depressed Anime Girls

Hotaru Tomoe from Sailor Moon is one of the saddest and most depressed anime girls ever. She was born into a wealthy family, but her parents were killed when she was younger.

Her only friend was her grandfather, who died when she was nine. After that, she was raised by her aunt and uncle, who were very strict with her. As a result, she grew up to be a timid and introverted girl.

When she was 14, she met Sailor Uranus and Sailor Neptune, who became her friends. However, they were killed in battle shortly afterward. This caused Hotaru to become even more withdrawn and depressed.

Later, she met Sailor Saturn, who told her she must sacrifice herself to save the world. Hotaru agreed to this, but it caused her great pain. In the end, she did manage to save the world, but at the cost of her own life.

9. LaLa-Ru from Ima Soro Ni Iru Boku

Depressed Anime Girls

LaLa-Ru’s story in “Ima Soro Ni Iru Boku” is a heartbreaking and emotional journey that touches the hearts of many anime fans.

She is a young girl with the power to control water, making her a valuable captive of a powerful and ruthless enemy. LaLa-Ru is subjected to unspeakable atrocities, leaving her with physical and emotional scars that haunt her.

Despite this, LaLa-Ru is an inspiring character who clings to hope and exhibits kindness and compassion toward others. Her story is a reminder of the power of resilience and the human spirit’s ability to endure and overcome even the most difficult circumstances.

LaLa-Ru’s journey toward healing and finding inner peace is a powerful reminder that love and empathy are essential to human connection and healing.

Her story is a touching example of how a character can leave a lasting impact on those who watch and cherish her.

Related: Anime Characters With Eye Patches: Top 20 You’ll Love

10. Sakura Matou from Fate/Stay Night

Depressed Anime Girls

Sakura Matou from Fate/Stay Night is one of the most tragic and depressing characters in all anime. Her story is one of unending pain, suffering, and heartbreak. She was born into a wealthy family, but her parents were killed when she was just a child.

Her grandfather took her in and raised her, but he was a cruel man who mistreated her and made her life a living hell.

When she was a teenager, Sakura was raped by her brother Shinji. This trauma would haunt her for the rest of her life.

Sakura would later meet and fall in love with Shirou Emiya, but their relationship was doomed. Shirou was already in love with another woman, Saber, and Sakura could never compete with her.

Sakura became nothing more than a pawn in Shirou’s quest to win the Holy Grail. This quest would cost Sakura her sanity, body, and life.

Sakura’s story is one of the saddest and most depressing in all anime. She is a character who has suffered endlessly, both mentally and physically. If you are looking for an anime girl who embodies sadness and despair, look no further than Sakura Matou.

11. Misuzu Kamio from Air

Depressed Anime Girls

Misuzu Kamio is a character from the anime series Air. She is a 12-year-old girl who has an unfortunate and depressing backstory.

Her mother died when she was young, and her father was never around. As a result, Misuzu has always felt alone and neglected.

One day, she meets a boy named Ryuuya, who helps her escape a challenging situation. From then on, Misuzu starts to open up more and forms a close bond with him. However, she is still plagued by her sadness and loneliness.

While Misuzu may not be the happiest anime girl, she is one of the saddest and most depressingly realistic. Her story will surely tug at your heartstrings and leave you feeling empathy for her plight.

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12. Hayami Kohinata from H2O Footprints in the Sand

Depressed Anime Girls

Hayami Kohinata is the female protagonist of H2O: Footprints in the Sand. She’s a kind and caring person, but she’s also deeply troubled by her past.

She was orphaned at a young age, and her only memories of her parents are of them dying in a car accident. Her grandparents raised her, but they’re both now deceased. As a result, Hayami has always felt alone in the world.

She began to distance herself from other people after her grandfather died and became even more withdrawn after her grandmother died.

Hayami stopped going to school and spent most of her time indoors. She eventually found solace in art and began expressing herself through painting.

Hayami’s paintings are often dark and depressing, reflecting her inner turmoil. However, she also paints beautiful landscapes and flowers, representing the hope she still holds onto.

Despite all that she’s been through, Hayami is still a kind and caring person. She just needs someone to reach out to her and help her heal from her past trauma.

13. Seras Victoria from Hellsing

Depressed Anime Girls

Seras Victoria from Hellsing is one of the most tragic and depressing characters in all of anime. She was turned into a Her bloodlust torments herstruggled to come to terms with what she has become ever since.

She is tormented by her bloodlust and often feels like a monster. Even though she has the strength and power of a vampire, she is still just a human girl at heart.

Seras has faced a lot of tragedy in her life. She was orphaned at a young age and then raped by a group of men. After being turned into a vampire, she was forced to kill her own father.

All of this has taken a toll on her mental state. As a result, she is often sad and depressed. However, she tries to hide her feelings behind a tough exterior.

Despite all of her life’s darkness, Seras can still find moments of happiness. Her relationship with Alucard is one of the brightest parts of her existence.

He has shown her compassion and understanding, which has helped her to cope with what she is going through.

Additionally, she has made friends with some other characters in Hellsing, providing some much-needed levity in an otherwise dark series.

Even though Seras Victoria may be one of the saddest and most depressing characters in all anime, she is still someone we can root for.

Related: Anime Characters With Closed Eyes: Discover The Top 15

14. Mizore Shirayuki from Rosario to Vampire

Depressed Anime Girls

Mizore Shirayuki from Rosario to Vampire is one of the saddest and most depressing anime girls ever. Her story is one of unrequited love and heartbreak, and she always seems to be just out of reach of happiness.

Mizore is first introduced as a loner who keeps to herself at school. Her classmates bully her and have no friends to speak of.

The only thing that brings her joy is fantasizing about the day her crush, Tsukune Aono, will finally notice her.

Sadly, Mizore’s hopes are dashed when she sees Tsukune with another girl, Moka Akashiya. Tsukune will never return her feelings, and Mizore sinks into a deep depression.

She becomes even more withdrawn and starts skipping school. Her grades begin to slip, and she’s in danger of failing altogether. There’s nothing left for Mizore but a lifetime of loneliness and misery.

But then, in desperation, Mizore tries to kill herself. Thankfully, she’s saved by Tsukune and Moka, who finally see how much pain she’s in. They take her in and start helping her recover from her depression.

Slowly but surely, Mizore starts to open up again. She makes new friends and even begins to date someone. Although she still feels pain over her unrequited love for Tsukune.

15. Yuuko Kanoe from Tasogare Otome Amunejia

Depressed Anime Girls

Yuuko Kanoe is a character from the anime series “Tasogare Otome Amunejia,” and her story is a heart-wrenching tale of unreciprocated love and tragic loss.

Yuuko is a ghost who haunts her former school, and she is invisible to everyone except for one boy named Teiichi Niiya. Yuuko falls deeply in love with Teiichi, but their love is destined to remain unfulfilled due to their different states of existence.

Despite her tragic circumstances, Yuuko remains a strong and compassionate character who cares deeply for those around her. Her story is a poignant exploration of the themes of love, loss, and the enduring resilience of the human spirit.

Yuuko’s journey will surely strike a chord with anyone who has experienced the pain of unrequited love or the heartbreak of loss.

She is a character that anime fans will undoubtedly cherish and admire for her strength and courage in the face of unimaginable hardship.

Related: Anime Characters With Ice Powers: Meet The 12 Best

16. Rukia Kuchiki from Bleach

Depressed Anime Girls

Rukia Kuchiki is a fictional character in the popular manga and anime series Bleach. The series’ first story arc introduces her as a Soul Reaper or death god.

Rukia possesses limited powers compared to other Soul Reapers, and she transfers these abilities to the human protagonist Ichigo Kurosaki so that he can protect others from evil spirits.

During the series’ second story arc, Rukia is accused of a crime she did not commit and is sentenced to execution. Ichigo rescues her from this fate, but in doing so, she absorbs most of her powers, leaving her effectively human.

For the rest of the series, Rukia works alongside Ichigo as he strives to protect others and hone his own Soul Reaper abilities.

Rukia is a complex character who goes through considerable development over the course of Bleach. She starts out as somewhat aloof and distant but grows to care deeply for Ichigo and his friends.

Her selfless nature often puts her at odds with her superiors. Still, she always does what she believes is right regardless of the consequences.

Throughout the series, Rukia struggles with her identity as both a Soul Reaper and a human. She understands life’s value and learns to cherish even the simplest things.

This makes her one of the most relatable and sympathetic characters in Bleach, someone anyone can empathize with regardless of their situation in life.

17. Rei Ayanami from Neon Genesis Evangelion

Depressed Anime Girls

Rei Ayanami is the First Child, pilot of Evangelion Unit-00, and one of the main protagonists of Neon Genesis Evangelion. She is an enigmatic figure who rarely shows emotion and is often seen as a cold and detached person.

However, Rei is a kind and caring person with deep feelings for her friends and comrades. She also has a strong sense of duty and loyalty.

Rei’s backstory is tragic. She was born from the remains of Yui Ikari, who died during the Second Impact. As a result, she was raised by SEELE in secret and used as a tool to further their agenda. This experience emotionally scarred Rei, and it caused her to be distant from others.

Despite her tragic backstory, Rei is a strong and determined young woman. She has overcome great hardship in her life and continues to fight for what she believes in.

Rei is an inspiration to all who know her. She will continue to be one of the most popular characters in anime history.

18. Victorique de Blois from Gosick

Depressed Anime Girls

Victorique de Blois is a tragic figure in the anime series Gosick. Orphaned at a young age, she was raised in a strict boarding school where her classmates constantly ridiculed her. As a result, Victorique grew up to be a cold and aloof young woman.

While she may seem emotionless on the outside, Victorique is actually very caring and sensitive. She often uses her prodigious intelligence to help others, even if they don’t deserve it. Unfortunately, her good deeds are often met with betrayal and heartbreak.

Despite all the pain she’s endured, Victorique remains an optimist. She continues to believe in the goodness of people, even though they’ve let her down time and time again. This makes her one of the most tragic and heartbreaking characters in all of anime.

19. Nico Robin from One Piece

Depressed Anime Girls

Nico Robin is a complex and intriguing character in the popular anime and manga series, One Piece. While initially introduced as a criminal Baroque Works organization member, she quickly becomes a member of the Straw Hat Pirates and an integral part of their crew.

However, underneath her calm and collected exterior, Nico Robin is a tragic and depressed character. She has experienced tremendous loss and trauma throughout her life, including the destruction of her homeland and her mother’s death.

Despite this, she remains strong and stoic, rarely showing her emotions to others. We can see glimpses of her vulnerability and pain through her interactions with her crewmates.

Nico Robin’s character reminds us that even the strongest can carry deep wounds and scars. Her journey towards healing and finding a sense of belonging with the Straw Hat Pirates is a compelling and emotional arc that resonates with many series fans.

20. Yuki Nagato from Suzumiya Haruhi no Yuuutsu

Depressed Anime Girls

As a character, Yuki Nagato from Suzumiya Haruhi no Yuuutsu is an enigma. She rarely shows emotion, and when she does, it’s often in the form of deadpan sarcasm.

Her backstory is a mystery, and her motivations are often unclear. However, there is one thing that is very clear about Yuki Nagato: she is deeply sad and depressed.

Yuki’s sadness stems from her deep loneliness. She was created as an artificial human by a secret organization called the Data Overmind. As such, she has never truly been human.

She has no friends or family and feels incredibly alienated from the world around her. This isolation has led to a great deal of introspection on her part, and she has come to realize just how different she really is.

This realization only deepens her feelings of loneliness and despair. She feels like she will never be able to connect with anyone truly, and that her existence is ultimately meaningless.

These feelings are compounded by the fact that she is constantly forced to observe the happy lives of those around her while unable to experience them. It’s no wonder that Yuki Nagato is one of the most sad and depressed anime girls of all time.

21. Moeka Kiryu from Stein’s Gate

Depressed Anime Girls

There are few characters in the anime world as complex and interesting as Moeka Kiryu from Stein’s Gate. Despite her unassuming appearance, Kiryu is a deeply troubled individual struggling to come to terms with her dark past.

Born into a wealthy family, Kiryu was always expected to follow in her parent’s footsteps and become a successful businesswoman.

However, she could never live up to their expectations and instead found herself working menial jobs and living in poverty. During this time, she met Okabe Rintaro, a self-proclaimed “mad scientist” who would change her life forever.

Okabe convinced Kiryu to help him with his research into time travel, and she soon became obsessed with using technology to change her past.

This led her down a dark path, and she eventually became one of the key members of the shadowy organization known as SERN.

Kiryu’s obsession with time travel ultimately leads to her downfall, and she ends up being responsible for the death of Okabe’s beloved girlfriend, Makise Kurisu.

This tragedy plunged Kiryu into a deep depression, and she has been struggling to cope ever since.

While she may not be the happiest character on this list, Kiryu’s story is nonetheless intriguing and tragic. Her struggles offer a unique insight into the human condition. She remains one of the most Sad & Depressed Anime Girls.

22. Iwakura Lain from Serial Experiment Lain

Depressed Anime Girls

Iwakura Lain may not be the first girl on this list, but she is undoubtedly one of the most memorable. Lain is the protagonist of Serial Experiment Lain. This enigmatic and mind-bending anime explores the nature of reality and our relationship to technology.

Lain is a shy and introverted 14-year-old girl who is thrust into a world of mystery and intrigue when she starts receiving strange emails from someone called the “Wired.”

As Lain becomes more involved with Wired, she starts to change, becoming more confident and assertive. However, these changes come at a cost, and Lain loses touch with reality.

While Lain’s transformation may sometimes be disturbing, it’s also compelling and thought-provoking. Her journey is a fascinating exploration of what it means to be human in a world that is increasingly dominated by technology.

23. Yukari Yukino from The Garden of Words and Kimi no Na was

Depressed Anime Girls

Yukari Yukino from The Garden of Words is a classic anime girl who is down on her luck. She’s lost her job, she’s in debt, and she’s generally just feeling sorry for herself.

But when she meets a young man named Ryōta, everything changes. Ryōta helps Yukari see the beauty in life again, and the two of them form a deep bond. Yukari is a sad girl, but she’s also incredibly strong.

Kimi no Na wa is a newer anime that tells the story of two teens who swap bodies. Taki is a boy who loves his life in Tokyo, while Mitsuha is a girl who wishes she could live in the city.

When they switch places, they must learn to adapt to each other’s lives. It’s not easy, but it’s worth it because they get to understand each other in a way they could never have before. Kimi no Na wa is a sad anime, but it’s also incredibly beautiful and heartwarming.

24. Mamimi Samejima from FLCL

Depressed Anime Girls

Mamimi Samejima from FLCL is perhaps one of the most relatable characters on this list. She’s a high school student who’s just trying to get through the day, but she’s burdened by the fact that she doesn’t really have anyone to talk to. Her only outlet is her imaginary friend, an alien named Canti.

Mamimi is often seen wandering around town, smoking cigarettes, and looking sad. Clearly, she’s not happy with her life, but she doesn’t really know how to change it.

She feels trapped and alone but doesn’t want to reach out for help because she doesn’t think anyone would understand her.

Despite all of her problems, Mamimi is still a kind and caring person. She looks out for those around her, even if she doesn’t really know them.

And although she may not be able to fix her own life, she can at least try to make the lives of those around her a little bit better.

25. Hanabi Yasuraoka from Scum’s Wish

Depressed Anime Girls

Hanabi Yasuraoka truly embodies the phrase “scum of the earth.” She’s manipulative, selfish, and downright cruel to those around her to get what she wants. And what she wants is to be loved.

Hanabi will stop at nothing to make the object of her affection (Mugi Awaya) love her back, even if it means destroying the lives of everyone around them.

While Hanabi may seem like a heartless monster, there’s more to her than meets the eye. Underneath her cold exterior is a girl who’s desperately searching for someone to love her.

She’s been hurt so many times before that she doesn’t know how to trust or love anymore. As a result, she takes out all her pain and frustration on those around her.

Suppose you’re looking for an anime girl who’s both complex and deeply flawed. In that case, Hanabi Yasuraoka from Scum’s Wish is definitely one to check out.

26. Tomoko Kuroki from Watashi ga Motenai no wa Dou Kangaetemo Omaera ga Warui

Depressed Anime Girls

Tomoko Kuroki is the perfect example of an anime girl who is sad and depressed. She comes from the manga and anime series Watashi ga Motenai no wa Dou Kangaetemo Omaera ga Warui, which translates to “No Matter How I Look at It, It’s You Guys’ Fault I’m Not Popular!”.

The series is based on a light novel by the same name and follows Tomoko as she tries to become popular in high school.

Unfortunately for Tomoko, things don’t always go her way. She’s often made fun of by her classmates and is generally considered to be a social outcast. As a result, she struggles with depression and low self-esteem.

Despite her challenges, Tomoko remains a likable character. She’s funny, relatable, and ultimately just trying to find her place in the world. If you’re looking for an anime girl who understands your pain, look no further than Tomoko Kuroki.

27. Shirahoshi, “Mermaid Princess” from One Piece

Depressed Anime Girls

Shirahoshi is a beloved character from One Piece, known as the Mermaid Princess. Her life is filled with sadness and isolation, despite being a member of royalty as the daughter of King Neptune.

Her unique ability to communicate with the Sea Kings, powerful creatures that inhabit the deep sea, only adds to her mystique.

Sadly, Shirahoshi has spent most of her life confined to the safety of her palace. Humans and pirates pose a significant danger, making it impossible for her to explore the outside world.

This isolation has left her feeling powerless and hopeless, struggling to find meaning and purpose in her life.

Thankfully, Shirahoshi’s story takes a turn when she interacts with the Straw Hat Pirates. Through these interactions, she gains confidence and a sense of agency.

Her journey toward finding her place in the world is compelling and emotional, reminding her of the impact loneliness can have on a person’s mental health. It’s no wonder her character resonates so deeply with fans of the series.

28. Erza Scarlet from Fairy Tail

Depressed Anime Girls

Erza Scarlet is a complex and layered character from the popular anime series Fairy Tail. While known for her strength and resilience, Erza has also had her fair share of struggles and moments of sadness and depression throughout the series.

Despite her powerful abilities as a mage, Erza’s traumatic past haunts her, leaving her struggling with trust issues and a fear of abandonment.

Her emotions are further complicated by her role as a leader in the Fairy Tail guild, causing her to feel pressure to appear strong and in control at all times.

Erza’s journey toward healing and self-discovery is a central theme in the series. Her struggles with depression and sadness are a poignant reminder of the importance of mental health.

Her character inspires fans, showcasing the strength and resilience it takes to overcome life’s challenges and emerge stronger on the other side.

29. Tsubaki from Mirai Nikki

Depressed Anime Girls

Tsubaki from Mirai Nikki is a character whose life is filled with sadness and isolation. She is one of the diary holders in the survival game that the series revolves around, possessing the ability to see the future and manipulate others’ emotions.

Despite her power, Tsubaki is a lonely and depressed character, having spent most of her life confined to her family’s shrine. Her duty to the shrine and the weight of her family’s expectations leave her feeling trapped and helpless.

Tsubaki’s character is a poignant reminder of familial pressure’s impact on a person’s mental health. Her journey toward self-discovery and finding her own path in life is a compelling and emotional story that resonates with many fans of the series.

Despite her challenges, Tsubaki’s strength and resilience inspire viewers, demonstrating the importance of staying true to oneself and finding one’s own path in life.

30. Yayoi Kise From Smile Pretty Cure!

Depressed Anime Girls

Yayoi Kise is a character from Smile Pretty Cure! who initially struggles with feelings of sadness and loneliness. She is a shy and introverted girl who finds connecting with others and expressing her emotions challenging.

Yayoi’s struggles with self-confidence and a sense of inadequacy make it difficult for her to pursue her dreams or make friends.

However, as the series progresses, Yayoi gains confidence and develops her talents as an artist, discovering her unique strengths and abilities.

Yayoi’s character serves as a poignant reminder of the importance of self-love and self-acceptance. Her journey toward finding her place in the world and embracing her identity is an inspiring story that resonates with many series fans.

Her character is a shining example of the power of perseverance and self-belief. Her growth and development throughout the series make her a beloved and relatable character for many viewers.


Sad and depressed anime girls have become relatable to audiences globally, serving as poignant reminders of people’s mental health challenges.

While their stories can be emotional, these characters offer inspiration and hope. They show us that overcoming struggles and finding our place in the world is possible.

Their portrayal with sensitivity and nuance shows society’s evolving attitudes toward mental health. As we prioritize mental health awareness and support, these characters will continue to be a significant part of popular culture, encouraging us to be kinder to ourselves and each other.

In short, depicting sad and depressed anime girls resonates with audiences worldwide and inspires us to prioritize mental health and self-discovery.