2000s Cartoon Mania: The Ultimate List of the 35 Best

Are you feeling nostalgic and yearning to revisit the whimsical world of the 2000s? Then you’ve stumbled upon the perfect treasure trove.

Our “2000s Cartoon Mania: The Ultimate List of the 35 Best” is a curated time capsule that will transport you back to an era filled with animation marvels. From Saturday morning rituals to after-school unwinding sessions, these beloved cartoons helped shape a generation.

Prepare to reminisce on some classic gems, discover overlooked masterpieces, and reignite your love for this imaginative era of animation. Let’s take an animated stroll down memory lane to revisit the 2000s cartoon phenomenon, shall we?

Must-Watch 2000s Cartoon

In this section, we dive headfirst into our definitive compilation of the finest cartoons the 2000s had to offer. Each entry represents a distinct chapter of this dynamic decade, from superheroes saving the day to aliens exploring Earth.

Buckle up as we embark on a journey through the most unforgettable and cherished 2000s cartoons!

1. Avatar: The Last Airbender (2005-2008)

Avatar: The Last Airbender (2005-2008)

Set in a world where people can control the four elements – water, earth, fire, and air, Avatar is a masterstroke of storytelling that captivated viewers of all ages. It follows Aang, the titular Avatar and the last of his kind, as he embarks on an epic journey to end a century-long war.

With its distinctive blend of anime-inspired visuals, intricate world-building, and emotionally profound narratives, the show delves into mature themes of war, peace, and personal responsibility. Its richly developed characters and poignant narrative arcs made Avatar: The Last Airbender an enduring symbol of 2000s cartoons.

2. Ben 10 (2005-2008)

Ben 10 (2005-2008)

An adventure-packed series that brought us Ben Tennyson, a 10-year-old boy with the power to transform into 10 different alien superheroes using a mysterious watch-like device called the Omnitrix.

With each alien form offering unique powers and abilities, Ben and his cousins faced alien threats, fought supervillains, and saved the world countless times. Ben 10 stands as an emblem of 2000s animation, balancing excitement and humor, loved for its fun-filled action, relatable characters, and intriguing storyline.

3. Teen Titans (2003-2006)

Teen Titans (2003-2006)

This groundbreaking series featured five adolescent superheroes – Robin, Starfire, Cyborg, Beast Boy, and Raven, navigating the trials of being a teenager while combating evil forces.

Teen Titans offered a winning mix of humor, drama, and action and was notable for its anime-influenced animation and complex themes. With character development at its heart, the series explored identity, friendship, and responsibility issues, making it a beloved staple of 2000s cartoons.

4. Samurai Jack (2001-2004, 2017)

Samurai Jack (2001-2004, 2017)

A tale of time travel, heroism, and relentless pursuit of justice, Samurai Jack followed a feudal-era samurai hurled into a dystopian future ruled by the malevolent shape-shifter Aku.

With its cinematic storytelling, minimal dialogue, and beautifully stylized animation, Samurai Jack pushed the boundaries of what a cartoon could achieve. Its innovative blend of different cultures and genres and its philosophical undertones made it a revolutionary entry in the 2000s cartoon scene.

5. The Fairly OddParents (2001-2017)

The Fairly OddParents (2001-2017)

Enter the whimsical world of Timmy Turner, a 10-year-old boy with two fairy godparents who grant his every wish. This series cleverly used magical escapades to explore real-world problems, from school troubles to family issues.

The Fairly OddParents was known for its zany humor, vibrant animation, and lovable characters, offering a delightful take on the “be careful what you wish for” motif. Its quirky charm and inventive storytelling made it one of the most entertaining and endearing cartoons of the 2000s.

6. Kim Possible (2002-2007)

Kim Possible (2002-2007)

High school cheerleader by day, international crime-fighter by night – that’s Kim Possible in a nutshell. This unique animated series flawlessly blends teenage drama with high-octane spy adventures.

Kim, along with her clumsy yet loyal sidekick Ron Stoppable and his naked mole-rat Rufus, thwarts evil masterminds while navigating typical adolescent issues. Its captivating characters, humor-laden dialogues, and empowering representation of a female lead make Kim Possible an unforgettable part of 2000s animation history.

7. Phineas and Ferb (2007-2015)

Phineas and Ferb (2007-2015)

Ever wondered what to do with 104 days of summer vacation? Just ask Phineas and Ferb! This ingenious series follows the stepbrothers as they embark on outlandish adventures in their backyard while their pet platypus Perry leads a double life as a secret agent.

Known for its catchy musical numbers, memorable characters, and its smart, satirical humor, Phineas and Ferb showcases the boundless realms of creativity and imagination, making it a true gem of 2000s cartoons.

8. Wolverine And The X-Men (2008–2009)

Wolverine And The X-Men (2008–2009)

Delving into the complex universe of Marvel’s X-Men, this series brings a fresh take on beloved characters with Wolverine at the helm. After the X-Men disband following a catastrophic event, Wolverine must reunite the team to save both the mutant and human species.

It strikes a perfect balance between showcasing individual character arcs and the larger narrative of mutant survival, making it a standout series of the 2000s for comic book fans and new viewers.

9. The Spectacular Spider-Man (2008-2009)

The Spectacular Spider-Man (2008-2009)

This show delivers a riveting portrayal of Spider-Man’s early days. It follows Peter Parker, a brilliant high-schooler juggling his double life as an ordinary teen and the web-slinging superhero, Spider-Man.

By successfully integrating Peter’s school life, personal dilemmas, and crime-fighting escapades, The Spectacular Spider-Man presents an authentic and relatable character study that has earned its place as a fan-favorite among 2000s superhero cartoons.

10. Danny Phantom (2004-2007)

Danny Phantom (2004-2007)

This series takes us on an ethereal adventure with Danny Fenton, a teenage boy who becomes a half-ghost superhero after an accident in his parents’ ghost lab.

With the power to phase through walls, turn invisible, and fly, Danny fights to protect his town from spectral threats. Its unique concept, engaging storylines, and well-rounded main character make Danny Phantom a memorable and intriguing cartoon of the 2000s.

11. Spongebob Squarepants (1999-present)

Spongebob Squarepants (1999-present)

An unforgettable staple of 2000s animation, this series introduces us to the endearing Spongebob Squarepants, a hyperactive and optimistic sea sponge living in a pineapple under the sea in Bikini Bottom. Though seemingly childlike, its humor appeals to a broad demographic due to its clever wit and often subtle commentary.

From Squidward’s sarcasm to Patrick’s silliness, each character contributes to the show’s irresistible charm. With its quirky humor, memorable catchphrases, and iconic characters, Spongebob Squarepants is undoubtedly a cultural phenomenon that continues to captivate audiences.

12. Megas XLR (2004–2005)

Megas XLR (2004–2005)

Megas XLR is an homage to everything great about the 80s and 90s pop culture wrapped in a mecha-style animated series. It follows the exploits of Coop, a video game fanatic who accidentally becomes the pilot of a giant robot from the future.

The show has rock music, retro gaming, and hot rod culture references. Megas XLR stands out for its distinctive animation style, tongue-in-cheek humor, and its unique blend of action and comedy, making it a cult classic among 2000s cartoons.

13. Invader Zim (2001–2006)

Invader Zim (2001–2006)

With its dark humor, stylized animation, and surreal storylines, Invader Zim took the 2000s animation scene by storm. It chronicles the misadventures of Zim, an alien from planet Irk, sent to Earth on a faux mission to conquer it.

Despite its brief run, it gained a dedicated fanbase for its unique blend of science fiction, horror, and satirical commentary on society, making it a standout among 2000s cartoons.

14. Justice League (2001–2004)

Justice League (2001–2004)

Building on the success of the Batman and Superman animated series, Justice League brings together DC’s most iconic superheroes. Superman, Batman, Wonder Woman, The Flash, Green Lantern, Hawkgirl, and Martian Manhunter team up to protect Earth from supernatural threats.

The series is lauded for its mature storytelling, well-developed characters, and epic action sequences. Justice League has been a cornerstone of 2000s animation and one of the most influential superhero cartoons ever made.

15. 6teen (2004-2010)

6teen (2004-2010)

A relatable portrayal of teenage life, 6teen revolves around six 16-year-old friends navigating through their first part-time jobs and lives away from parental guidance.

Set in a gigantic shopping mall, the series strikes a chord with viewers for its focus on the trials and tribulations of adolescence. Its blend of comedy, drama, and a pinch of romance, along with its genuine depiction of friendship, make 6teen a standout among the teen-oriented cartoons of the 2000s.

16. Cyberchase (2002-present)

Cyberchase (2002-present)

Uniquely combining education with entertainment, Cyberchase follows three kids who are transported into cyberspace. They thwart the evil Hacker with their cyber-bird friend using their math and problem-solving skills.

With its vibrant animation, engaging storylines, and well-integrated educational content, Cyberchase is a brilliant 2000s cartoon that made learning mathematics fun and exciting.

17. The Grim Adventures of Billy & Mandy (2003 – 2007)

The Grim Adventures of Billy & Mandy (2003 – 2007)

This dark comedy cartoon revolves around the unlikely friendship between two children, Billy and Mandy, and Grim, the Grim Reaper. After losing a game, Grim becomes their best friend and is involved in their wacky adventures.

The series’ offbeat humor, outlandish scenarios, and clever writing make it a standout in the landscape of 2000s cartoons, offering laughs and chills in equal measure.

18. House Of Mouse (2001–2003)

House Of Mouse (2001–2003)

In this unique series, Mickey Mouse plays the nightclub owner, where classic Disney characters gather to enjoy animated shorts. Each episode delivers a blend of new modern animations and older classics, creating a fun, nostalgic trip for Disney fans.

House of Mouse’s charm lies in celebrating Disney’s rich animated history, making it a delightful entry in 2000s cartoons.

19. Codename: Kids Next Door – 2002-2008

Codename: Kids Next Door – 2002-2008

This series celebrates the spirit of childhood adventures and imagination, following a group of kids forming a secret organization to fight adult tyranny.

Each kid, known by their codename (Numbuh One, Two, and so on), brings a unique personality and skill set to the team. Its quirky humor, thrilling adventures, and relatable themes of camaraderie made it a fan-favorite among 2000s cartoons.

20. Foster’s Home For Imaginary Friends (2004–2009)

Foster’s Home For Imaginary Friends (2004–2009)

A vibrant exploration of childhood imagination, this series introduces us to a world where imaginary friends are real and live in a foster home once children outgrow them. We follow a boy named Mac and his best friend, Bloo, on their daily adventures in the foster home.

The series’ distinctive animation style, colorful characters, and touching narrative made it a standout show, earning it a special place in the annals of 2000s cartoons.

21. The Proud Family (2001 – 2005)

The Proud Family (2001 – 2005)

Celebrating diversity and family, The Proud Family stands out for its portrayal of an African-American family navigating everyday life. The series revolves around Penny Proud, a 14-year-old girl juggling her teenage life, her quirky family, and her friends.

It combines humor, heart, and important life lessons, making it an important cartoon of the 2000s that tackled social and cultural issues with grace and sensitivity.

22. Ed, Edd N Eddy (1999 – 2008)

Ed, Edd N Eddy (1999 – 2008)

Chronicling the misadventures of three friends, Ed, Edd (aka Double D), and Eddy, this series is a delightful ode to suburban childhood and the joy of simpler times.

Whether it’s about making money for jawbreakers or dealing with neighborhood kids, their antics keep the viewers engaged. Known for its slapstick humor, eccentric characters, and unique hand-drawn animation, Ed, Edd N Eddy holds a cherished spot in the annals of 2000s animation.

23. CatDog (1998 – 2005)

CatDog (1998 – 2005)

CatDog explores the unique existence of a conjoined twin hybrid of a cat and a dog. With Cat’s sophistication and Dog’s fun-loving nature, the show capitalizes on their contrasting personalities, leading to hilarious and sometimes chaotic situations.

Its peculiar premise, memorable characters, and slapstick humor make CatDog an unforgettable and distinctive piece of 2000s animation.

24. Duck Dodgers (2003–2005)

Duck Dodgers (2003–2005)

An ingenious spin-off of the classic Looney Tunes, this series follows Daffy Duck (as Duck Dodgers) and Porky Pig (as the Eager Young Space Cadet) in a far-flung future where they have absurd space adventures.

With its nostalgic characters in a new sci-fi setting, quick-witted humor, and clever pop culture references, Duck Dodgers has carved a unique niche in 2000s cartoons.

25. The Powerpuff Girls (1998 – 2005)

The Powerpuff Girls (1998 – 2005)

This iconic series centers around three kindergarten-aged girls, Blossom, Bubbles, and Buttercup, who are bestowed with superpowers. They balance their everyday little girl activities with the responsibility to protect Townsville from villains.

Known for its vibrant animation, strong female characters, and clever balance of action and humor, The Powerpuff Girls remains a beloved series that significantly influenced 2000s animation.

26. Dragon Tales (1999–2005)

Dragon Tales (1999–2005)

Dragon Tales invites viewers into the fantastical world of Dragon Land, where a magical dragon scale transports siblings Emmy and Max. They share adventures with dragon friends, learning important life lessons along the way.

The series combines the excitement of dragon adventures with age-appropriate educational content, dealing with topics like conflict resolution, friendship, and empathy. Its vibrant animation, catchy tunes, and positive messages make it a significant 2000s cartoon, especially for younger audiences.

27. As Told By Ginger (2000 – 2006)

As Told By Ginger (2000 – 2006)

This series provides a realistic and nuanced portrayal of middle-school life through the lens of the compassionate and insightful Ginger Foutley. Ginger, along with her close friends, navigates the joys and challenges of teenage life.

Told By Ginger is widely praised for its mature narrative, character development, and tackling serious themes, making it a standout show in 2000s animation.

28. My Life As a Teenage Robot (2003 – 2009)

My Life As a Teenage Robot (2003 – 2009)

This inventive series follows XJ-9 (or Jenny), a powerful robot designed to protect Earth who desires to live as a normal teenager. Balancing high-school life and her duty as a superhero, Jenny’s adventures provide action-packed entertainment.

The show is notable for its unique art deco-inspired animation, charming characters, and the delicate balance between teenage drama and sci-fi action, securing its place in the annals of 2000s cartoons.

29. Dave the Barbarian (2004-2005)

Dave the Barbarian (2004-2005)

Set in the Middle Ages, this cartoon focuses on the misadventures of Dave, a muscular but cowardly barbarian, his princess sisters, and their peculiar family. Despite being a barbarian, Dave is more interested in gourmet cooking and poetry.

With its clever humor, delightful absurdity, and unconventional characters, Dave the Barbarian offers a fresh take on the fantasy genre and remains a unique addition to the 2000s cartoon lineup.

30. Star Wars: Clone Wars (2003–2005)

Star Wars: Clone Wars (2003–2005)

Serving as a bridge between Episode II and III of the Star Wars saga, Clone Wars brings epic space opera into the animated world. It follows Jedi Knights Anakin Skywalker and Obi-Wan Kenobi battling against the dark forces during the galactic civil war.

Praised for its breathtaking action sequences, compelling storylines, and expressive animation, Star Wars: Clone Wars adds depth to the Star Wars canon and is a memorable part of 2000s animation.

31. Totally Spies! (2001–2014)

Totally Spies! (2001–2014)

Blending teen drama with a spy thriller, Totally Spies! Follows high school girls Sam, Clover, and Alex, who lead double lives as spies for WOOHP (World Organization Of Human Protection).

The series is distinguished by its clever mix of teenage issues and high-stakes spy missions, all laced with humor and friendship. With its colorful animation, memorable characters, and empowering representation of female protagonists, Totally Spies! Holds a special place in the 2000s cartoon landscape.

32. What’s New Scooby-Doo? (2002 – 2006)

What’s New Scooby-Doo? (2002 – 2006)

The beloved mystery-solving dog and his gang returned in the 2000s with this series, promising more fun-filled, spine-tingling adventures. The gang traveled to exotic locations, unraveling paranormal mysteries with their renowned blend of comedy and suspense.

The show retained the classic charm of the original series while incorporating contemporary themes, thus resonating with a new generation of viewers and securing its place among the best 2000s cartoons.

33. Dora The Explorer (2000–2019)

Dora The Explorer (2000–2019)

This educational animated series follows the adventure-loving Dora, her monkey Boots, and their talking backpack as they explore different locations, solve puzzles, and learn Spanish vocabulary along the way.

Its interactive format, engaging storytelling, and positive life lessons made Dora the Explorer a cultural phenomenon and an invaluable part of children’s programming in the 2000s.

34. Bounty Hamster (2003–2004)

Bounty Hamster (2003–2004)

In this series, we follow the young girl Cassie and her companion Marion, a tough, one-eyed, talking blue hamster who happens to be an intergalactic bounty hunter. Together, they travel through space to find Cassie’s missing father.

Known for its charming characters, humorous dialogue, and exciting space adventures, Bounty Hamster is an under-the-radar gem of the 2000s cartoons.

35. Tutenstein (2003–2007)

Tutenstein (2003–2007)

A unique blend of history and fantasy, Tutenstein introduces us to a 10-year-old mummy, Tutankhensetamun (aka Tutenstein), who is brought back to life in a modern museum. With his friend Cleo and her cat Luxor, he navigates through modern life while dealing with ancient Egyptian curses and gods.

The series is appreciated for its detailed depiction of ancient Egyptian mythology, engaging storytelling, and comedic elements, making it a memorable inclusion in the lineup of 2000s cartoons.

Final Thoughts

As we wrap up our nostalgia-fueled journey, it’s clear that the 2000s were a golden era for cartoons.

With a spectrum of genres and styles, these animated treasures offer something for everyone, from high-stakes adventures in “Avatar: The Last Airbender” and “Ben 10”, to the unique humor in “Ed, Edd n Eddy” and “The Fairly OddParents”, and even educational content like “Dora the Explorer” and “Cyberchase”.

These 35 cartoons are truly the creme de la creme of their time, shaping childhoods, inspiring creativity, and leaving lasting impacts. Here’s to celebrating these unforgettable gems of the 2000s Cartoon Mania!